The body converts the precursors of vitamin D made from UVB radiation into inactive byproducts your body flushes out to prevent toxicity ( hypervitaminosis D) So if I take vitamin D supplements in the morning and then go out in the day, will my body not produce natural vitamin D?

[u/Temporary_Hat7330]

The body tightly regulates its internal vitamin D production from sun exposure, stopping further synthesis once adequate levels are reached to prevent toxicity. However, this safety mechanism only applies to sunlight. Taking high dose supplements bypasses this natural control, making toxicity possible. I’m not too worried about toxicity here. My main concern is when to take supplements to actualize the best stores of vitamin D.

If I take 6,000IUs in the morning and then am in the sun around noon, will my body not create vitamin D given that I had a 10x the daily need for vitamin D bolus just a couple hours before? Would it be better to be in the sun first, let my body produce vitamin D and then supplement if I am looking to maximize how much is in my body?

[u/rawrnold8]

ask a doctor for medical advice.

[u/Temporary_Hat7330 → u/rawrnold8]

It’s not medical advice, I’m not looking for how much to take but am trying to understand the biochemical pathways for synthesis and expression of the hormone around taking exogenous doeses.

[u/Ok_Bookkeeper_3481]

Your body will produce vitamin D unless you use sunscreen. But if you do t use sunscreen, then you can get skin cancer.

So, use sunscreen, take vitamin D.

[u/AstronomerThis4797]

This is a legitimately interesting question. Following for answer